Possible side effects vary from person to person. Everyone responds to medicines differently, especially if a patient is receiving... treatment in tandem with other prescription medications. Common side effects of GIP + GLP-1 Combo are most apparent during the initial stages of treatment, such as nausea, decreased appetite, diarrhea, indigestion, and others. However, these side effects gradually diminish over time. Please consult first with Dr. Nanda or your personal health care provider to discuss if GIP + GLP-1 Combo is the best treatment option for you.